EWAS Catalog

The 'EWAS Catalog' is a comprehensive database of epigenome-wide association studies (EWAS) that focus on the relationships between traits, exposures, and DNA methylation at numerous CpG sites across the human genome. This database is manually curated to compile associations between specific traits or exposures and DNA methylation patterns, requiring a significant level of statistical significance (p<1x10^-7).

Key features and highlights of the EWAS Catalog include:
1. Broad Data Coverage: The database encompasses a wide range of traits, exposures, and their associations with DNA methylation at CpG sites, making it a valuable resource for researchers in various fields, including genetics, epidemiology, and epigenetics.
2. Data Curation: The catalog undergoes careful manual curation to ensure the quality and reliability of the associations. This curation process involves reviewing the methodology, statistical significance, and key findings of each EWAS.
3. User Accessibility: The catalog provides a user-friendly interface, allowing researchers to search for specific trait-exposure associations and explore detailed information related to CpG sites and their connections to traits.
4. Research and Exploration: Researchers can use the database to investigate associations between traits/exposures and DNA methylation in a systematic and data-driven manner.
5. Collaboration and Data Sharing: The catalog serves as a valuable tool for researchers looking to collaborate, share data, and leverage existing findings in their own studies.